2 Responses to “Low Calorie/Low Fat Diets”

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  1. avatar Clive Last says:

    Given that you say that there is no good or bad cholesterol, just cholesterol, do you think that it is dangerous to health to have a high cholesterol level?

  2. avatar Zoë says:

    Hi Clive – so sorry it took so long to approve your comment – my comment alert stopped working for some reason late summer. I thought I’d manually caught them all, but sadly not.

    Good question – I’m open minded to Familial Hypercholesterolemia, as the extreme of high cholesterol. Uffe Ravnskov is confident that even with this condition, the high cholesterol per se is not a problem and his arguments are persuasive (see Ignore the Awkward). My take on FH is that we know this is defined as the situation where the LDL receptors don’t work properly and therefore the cells are not able to take the cholesterol for its vital work in the normal way and therefore the cholesterol stays in the blood stream, rather than getting to the cells where it is needed. In this case, the high blood cholesterol is the sign of the problem – the real problem is damaged cells that didn’t get the vital cholesterol.

    Given that only 1 in 500 people have FH, do I think high cholesterol is good generally? Absolutely. If you see this post (http://www.zoeharcombe.com/2010/11/cholesterol-heart-disease-%E2%80%93-there-is-a-relationship-but-it%E2%80%99s-not-what-you-think/) high cholesterol is associated with lower deaths for men and women for heart disease and all deaths. Cholesterol’s role is to protect and repair cells – it makes perfect sense it is helpful, not harmful.

    Finally – the body makes cholesterol and I don’t think that our bodies are trying to kill us. So, with one exception (coming in a second), our cholesterol level will be what it will be. It will be higher at the end of the winter in the absence of sunlight to synthesise cholesterol into vitamin D. It will be higher in pregnant women, who need a lot of cholesterol to make a healthy baby. It will be higher if we are injured or recovering from an illness or operation, as we will need extra for cell repair.

    The exception for when cholesterol can be unnaturally high is if we eat unnatural levels of carbohydrate. The starting substance from which the body makes cholesterol is a substance called Acetyl-CoA – this is also a by product of the Kreb’s cycle by which the body turns carbs into ATP (the body’s energy currency). Hence carbs can cause cholesterol to be unnaturally elevated. There are many studies on the impact of carbs on VLDL, but they rarely get heard above all the incorrect nonsense about fat and cholesterol. The biochemical pathway for the latter has not even been defined. We are told that fat increases cholesterol without even being told how it can, let alone that it does!

    Apologies for missing you again
    Very best wishes – Zoe

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